Research at the Diagnostic and Research Institute of Human Genetics covers a broad spectrum of important questions in the discipline of genetics.
Our research groups work on areas such as rare diseases and identification of their genetic causes, (tumor) cytogenetics, liquid biopsies and precision medicine as well as hereditary tumor syndromes and clinical teratology.
Our research projects are primarily application oriented since the focus is on the questions and needs of patients and individuals seeking counseling at our Genetic Counseling Center.
The goals of our research are to provide a diagnosis using state-of-the-art technology, to observe disease progression and to determine a prognosis and treatment options using sophisticated bioinformatics pipelines of genetic data sets.
Hereditary tumor predisposition syndromes: Our group focuses on investigating the genetic causes and consequences of potential hereditary tumor syndromes.
Complex genomics: The team explores the molecular mechanisms of monogenic and complex genetic disorders.
Rare Diseases: Our goal is to create the basis for a better understanding of rare diseases, further medical care and (development of) therapy by identifying their causes.
Liquid Biopsy: The goal of our group is to develop and apply innovative methods to identify pathological and physiological conditions from cell-free DNA in the blood circulation of humans.
Precision Medicine: We use bioinformatics to derive individualized optimal treatment strategies from data generated with next-generation sequencing (NGS).
